Dermatitis herpetiformis is associated with:-
Correct Answer: Transglutaminase 3
Description: Dermatitis herpetiformis is a gluten hypersensitivity condition C/F: lesions mainly over extensors, vesico papule lesions, extremely pruritic-resulting in excoriation marks, some patients might also develop fluid filled lesion DIF Finding: shows granular IgA deposits in the tip of dermal papillae giving picket fence appearance Epidermal transglutaminase (TG3) is the epidermal antigen for IgA deposited in the skin and Tissue transglutaminase (TG2) is the tissue antigen for IgA deposited in the small bowel mucosa which is associated with celiac disease. Initially patients TG2 is targeted later on these patients have skin involvement dermatitis herpetiformis targeting TG3
Category:
Dental
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now