Patient a known case off alcohol dependence after 3 days of last drink develops change in behaviour that he says he could see 5 cm people throwing stones at him, acts as if he is working in his workshop, frightened pacing in and out of the house with worsening more in the night. The possible diagnosis is delirium tremens.Treatment for the above mentioned patient

**Core Concept**
Delirium tremens (DTs) is a severe form of alcohol withdrawal characterized by sudden and severe changes in mental status, including confusion, agitation, and hallucinations. It typically occurs 48-72 hours after the last drink in individuals with a history of chronic alcohol use.

**Why the Correct Answer is Right**
The treatment of choice for delirium tremens involves the administration of benzodiazepines, which help to reduce the severity of withdrawal symptoms and prevent seizures. Benzodiazepines, such as lorazepam or diazepam, work by enhancing the activity of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter that helps to calm down the hyperactive brain activity associated with DTs. In this case, the patient is likely to benefit from the administration of a benzodiazepine to manage his symptoms and prevent further complications.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because antipsychotics, such as haloperidol, can worsen DTs by blocking the action of dopamine and exacerbating the underlying withdrawal symptoms.
**Option B:** This option is incorrect because anticonvulsants, such as phenytoin, are not the primary treatment for DTs and may not be effective in managing the patient's symptoms.
**Option C:** This option is incorrect because barbiturates, such as phenobarbital, are not typically used to treat DTs and can actually worsen the patient's condition due to their sedative effects.

**Clinical Pearl / High-Yield Fact**
It's essential to note that the treatment of DTs requires close monitoring of the patient's vital signs, including heart rate, blood pressure, and respiratory rate, as well as regular assessments of their mental status and withdrawal symptoms.

**Correct Answer:** C.

✓ Correct Answer: C. Lorazepam