**Question:** Denominator in general fertility rate is -

A. Total number of females aged 15-49 years
B. Total number of births
C. Total number of females aged 15-49 years multiplied by 12
D. Total number of females aged 15-49 years

**Core Concept:** Fertility Rate is a measure of the number of live births per 1,000 females in a given age group. It is calculated as the numerator divided by the denominator.

**Why the Correct Answer is Right:** The denominator in the general fertility rate calculation represents the population at risk. In this case, the denominator is the total number of females aged 15-49 years (option D). This ensures that the result represents the number of live births per 1,000 females in this specific age group.

**Why Each Wrong Option is Incorrect:**

A. Total number of females aged 15-49 years (option A) is a part of the correct answer but not the whole denominator.
B. Total number of births (option B) is incorrect because it represents the numerator, not the denominator.
C. Total number of females aged 15-49 years multiplied by 12 (option C) is incorrect because it does not represent the population at risk and is not consistent with the standard calculation formula.

**Clinical Pearl:** The general fertility rate helps healthcare professionals and policymakers understand the reproductive health status of a population, enabling them to develop appropriate strategies for family planning and reproductive health promotion.

**Correct Answer:** D. Total number of females aged 15-49 years