A stenotic valve is removed from a 70-year-old man. The value demonstrates hard nodular masses heaped up within the sinuses of Valsalva. On microscopic section, the acellular masses stain darkly blue with hematoxylin and eosin. Which of the following is the MOST significant constituent of the masses?

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Vikas Bhardwaj
Medical Technologist, AIIMS New Delhi
Updated: Apr 17, 2026