**Core Concept**
The transmission of malaria by the Anopheles mosquito is a fundamental concept in tropical medicine, involving the life cycle of the Plasmodium parasite within the mosquito vector. This process involves the mosquito ingesting infected red blood cells from a human host, followed by the parasite's development within the mosquito's midgut and subsequent transmission to a new host through the mosquito's saliva during a blood meal.
**Why the Correct Answer is Right**
Sir Ronald Ross, a British physician and parasitologist, made a groundbreaking discovery in 1897 by demonstrating that malaria is transmitted by the bite of an infected female Anopheles mosquito. He observed the parasite's life cycle within the mosquito and its role in transmitting the disease to humans. Ross's work led to a deeper understanding of the parasite's biology and the development of effective control measures. The Anopheles mosquito's saliva contains a compound that facilitates the parasite's entry into the host's bloodstream.
**Why Each Wrong Option is Incorrect**
**Option A:** There is no notable figure associated with this option.
**Option B:** The discovery of malaria transmission by the Anopheles mosquito is not attributed to Louis Pasteur, who made significant contributions to vaccination and germ theory.
**Option C:** Patrick Manson, a Scottish physician, is credited with identifying the role of mosquitoes in transmitting filariasis, not malaria.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that the Anopheles mosquito's saliva contains a compound called sialic acid, which facilitates the parasite's entry into the host's bloodstream, highlighting the importance of mosquito saliva in malaria transmission.
**Correct Answer: C. Patrick Manson demonstrated the role of mosquitoes in transmitting filariasis, not malaria.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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