The pattern of change of disease trends of moality and morbidity where the pandemics infection are replaced by degenerative and man-made disorders, the main cause of morbidity and the most frequent cause of fatality is known as:

**Core Concept**
The question describes a shift in disease trends, where pandemics and infectious diseases are being replaced by non-communicable, degenerative disorders, and man-made hazards. This phenomenon is characterized by a significant change in the epidemiology of diseases.

**Why the Correct Answer is Right**
The correct answer is known as the "Transition Theory" or "Epidemiologic Transition." This theory proposes that as a society develops economically, the pattern of disease changes from a high infant mortality rate and high death rate from infectious diseases to a lower infant mortality rate and higher death rate from non-communicable diseases, such as heart disease, cancer, and stroke. This transition is driven by improvements in healthcare, sanitation, and living standards, which lead to a decrease in infectious disease mortality, but also an increase in chronic disease morbidity and mortality.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not relevant to the description of disease trends and epidemiologic transition.
* **Option B:** This option does not accurately describe the shift in disease trends from infectious to non-communicable diseases.
* **Option C:** This option is a distractor and does not relate to the concept of epidemiologic transition.

**Clinical Pearl / High-Yield Fact**
The epidemiologic transition is a critical concept in public health, as it highlights the need for healthcare systems to adapt to changing disease patterns and prioritize prevention and management of non-communicable diseases.

**Correct Answer:** C.

✓ Correct Answer: C. Epidemiological transition