**Core Concept**
Degeneration of myomas, also known as uterine fibroids, refers to the pathological changes that occur within these benign tumors. The degeneration process can be influenced by various factors, including the size and location of the fibroid, hormonal changes, and the body's natural aging process.

**Why the Correct Answer is Right**
The correct answer is related to the blood supply to the fibroid. Myomas are highly vascularized tumors, and their growth is dependent on a rich blood supply. However, as the fibroid grows, its blood supply may not be able to meet its increasing demands, leading to ischemia and subsequent degeneration. This process is more likely to start in the periphery of the fibroid, where the blood supply is poorest.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the degeneration process is not more likely to start from the center of the fibroid. The center of the fibroid is typically well-oxygenated and well-nourished due to its rich blood supply.
**Option B:** This option is incorrect because the degeneration process is not more likely to start from the surface of the fibroid. While the surface of the fibroid may experience some ischemia, it is not the primary site where degeneration is likely to occur.
**Option C:** This option is incorrect because the degeneration process is not more likely to start from the surrounding myometrium. While the surrounding myometrium may be affected by the degenerating fibroid, it is not the primary site where degeneration is likely to occur.

**Clinical Pearl / High-Yield Fact**
A key factor to remember is that degeneration of myomas is more common in larger fibroids, particularly those greater than 10 cm in diameter. Additionally, degeneration is more likely to occur in fibroids that are located in the lower uterine segment.

**Correct Answer:** C.