Deficiency of enzyme a-keto acid decarboxylase leading to a block in the metabolism of branch chain amino acids is observed in
Correct Answer: Maple syrup urine disease
Description: Maple syrup urine disease(MSUD) is due to increased activity of branched chain alpha ketoacid dehydrogenase(BCKAD) complex,a mitochondrial enzyme involved in degradation of branched chain amino acids(leucine,isoleucine, and valine).This enzyme has 4 subunits:E1alpha,E1beta,E2 and E3. Reference:Essential pediatrics-Ghai,8th edition,page no:652
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now