Biochemistry Deficiencies in the enzyme glucose-6-phosphatase are likely to lead to which of the following? A Decreased glucagon production B Decreased Skeletal Muscle Glycogen Accumulation C Hyperglycemia D Increased hepatic glycogen accumulation 💡 Explanation Deficiencies in the enzyme glucose-6-phosphatase are likely to lead to which of the following? ✓ Correct Answer: B. Decreased Skeletal Muscle Glycogen Accumulation