Defect leading to thalassemia lies in –
Correct Answer: Haemoglobin
Description: Disorders of haemoglobin
Disorders of haemoglobin may be of two types : -
1. The qualitative defect of haemoglobin (hemoglobinopathy)
Hemoglobinopathies are disorders of haemoglobin, characterized by a defect that results in the abnormal structure of one of the globin chain of haemoglobin.
Examples are - Sickle cell anemia, HbC, HbE, HbD-Punjab, HbO-Arab, Hb Lepore.
2. The quantitative defect of haemoglobin
These disorders are characterized by a defect that results in a decreased rate of synthesis of one of the globin chain of haemoglobin.
Example - Thalassemia
Category:
Pathology
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