**Core Concept**
de Quervain's disease is a stenosing tenosynovitis that affects the tendons on the thumb side of the wrist. It causes pain and tenderness, particularly when grasping or turning the wrist.
**Why the Correct Answer is Right**
The condition is characterized by inflammation of the tendons of the extensor pollicis brevis (EPB) and abductor pollicis longus (APL) muscles, which are responsible for thumb movement. The tendons pass through a narrow tunnel in the wrist, known as the first dorsal compartment, and inflammation of these tendons leads to pain and stiffness.
**Why Each Wrong Option is Incorrect**
* **Option A:** de Quervain's disease typically affects the tendons of the extensor pollicis longus (EPL) and extensor digitorum tendons, not the EPB and APL muscles.
* **Option B:** Trigger finger is a different condition that affects the flexor tendons of the finger, causing pain and stiffness when bending the finger.
* **Option C:** Intersection syndrome is a condition that affects the tendons of the forearm, causing pain and tenderness at the wrist and forearm.
**Clinical Pearl / High-Yield Fact**
de Quervain's disease is often associated with repetitive strain injuries, such as those experienced by people who frequently use their hands for activities like gardening or typing.
**Correct Answer: D. Abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons.**
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