Cytokine for activating macrophage and conveing to epitheloid cell or giant cell ?
Correct Answer: IFN gamma
Description: Ans. is 'd' i.e., IFN gamma Granulomatous inflammation is a form of chronic inflammation characterized by collections of activated macrophages, often with T lymphocytes, and sometimes associated with central necrosis. These granulomas are type IV hypersensitivity reaction that involves CD4-helper T-cells. Helper T-cells are activated by IL-2 and produce IFN-y (interferon gamma) the major cytokine of granulomatous inflammation. IFN-y induces formation of granuloma by conversion of activated macrophages into epitheloid cells and formation of giant cells by fusion of epithelial cells.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now