Pharmacology Cyclo-oxygenase-1 (COX-1) isoenzyme: A Is increased by inflammation B Is predominant mode of action of Indomethacin C Is increased by lipopolysaccharide ie G –ve endotoxin D Is NOT involved in gastric mucosal protection 💡 Explanation Cyclo-oxygenase-1 (COX-1) isoenzyme: ✓ Correct Answer: B. Is predominant mode of action of Indomethacin