CRP is an acute-phase protein in inflammatory processes. Which among the following is the expansion of ‘C’ in CRP?
Correct Answer: Capsular polysaccharide of pneumococcus
Description: "Acute-phase proteins" include C-reactive protein, 1-antitrypsin, haptoglobin, 1-acid glycoprotein, and fibrinogen. CRP, so named because it reacts with the C polysaccharide of pneumococci. The elevations of the levels of these proteins vary from as little as 50% to as much as 1000-fold in the case of CRP.CRP is used as a marker of tissue injury, infection, and inflammation, and there is considerable interest in its use as a predictor of ceain types of cardiovascular conditions secondary to atherosclerosis. It also can stimulate the classic complement pathway. Ref: Murray R.K., Jacob M., Varghese J. (2011). Chapter 50. Plasma Proteins & Immunoglobulins. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.
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