**Core Concept**
Corticobasal degeneration (CBD) is a rare, progressive neurodegenerative disorder characterized by the accumulation of tau protein in the brain, leading to the degeneration of neurons in the cerebral cortex and basal ganglia. This results in a range of cognitive, motor, and behavioral symptoms.

**Why the Correct Answer is Right**
Corticobasal degeneration is typically characterized by asymmetrical motor symptoms, such as apraxia, myoclonus, and rigidity, often accompanied by cognitive decline and dementia. The disease also often presents with alien limb syndrome, where a patient's limb moves involuntarily. The tau protein accumulation in CBD disrupts normal neuronal function, leading to these symptoms.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because corticobasal degeneration is indeed characterized by apraxia, which is a loss of coordination and purposeful movement.
**Option B:** This option is incorrect because myoclonus, which is a sudden, involuntary muscle contraction, is a common feature of CBD.
**Option C:** This option is incorrect because alien limb syndrome, where a patient's limb moves involuntarily, is a well-documented symptom of CBD.

**Clinical Pearl / High-Yield Fact**
It is essential to note that corticobasal degeneration often presents with asymmetrical motor symptoms, which can help differentiate it from other neurodegenerative disorders.

**Correct Answer: D.**