Corneal deposits are seen in all except –
## **Core Concept**
Corneal deposits can be associated with various conditions, including systemic diseases, corneal dystrophies, and as a side effect of certain medications. These deposits can be composed of different materials such as lipids, proteins, or drugs.
## **Why the Correct Answer is Right**
Chlorpromazine is a phenothiazine derivative used primarily as an antipsychotic medication. One of its notable side effects is the deposition of pigment in the cornea, leading to corneal pigmentation. This condition can occur with prolonged use of the medication. On the other hand, conditions like **Fuchs endothelial dystrophy**, **lattice corneal dystrophy**, and **amyloidosis** are known to cause corneal deposits due to the accumulation of specific substances within the cornea.
## **Why Each Wrong Option is Incorrect**
- **Option A (Chlorpromazine):** This is actually a correct association with corneal deposits; thus, it's not the answer we're looking for. Chlorpromazine can cause corneal pigmentation.
- **Option B (Fuchs endothelial dystrophy):** This condition involves the cornea and can lead to corneal edema and vision problems. It is associated with corneal changes but specifically involves the endothelium.
- **Option C (Lattice corneal dystrophy):** This is a type of corneal dystrophy characterized by the deposition of amyloid (a protein) within the cornea, leading to corneal opacities.
- **Option D (Amyloidosis):** This condition involves the deposition of amyloid, a particular protein, in various tissues of the body, including the cornea. Corneal involvement can manifest as deposits.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that while many systemic and local conditions can cause corneal deposits, drug-induced corneal deposits, such as those caused by chlorpromazine, are notable for their association with long-term medication use.
## **Correct Answer:** . Chlorpromazine