Conversion of Prothrombin to thrombin requires

Correct Answer: Va, Ca++
Description: In the presence of tissue phospholipids (PL) and calcium ions, activated Factor X (Xa) combines with Factor Va to form prothrombin activator which initiates the conversion of prothrombin to thrombin.Factor V, X, and XII are activated and involved in other steps of intrinsic pathway.Ref: Ganong&;s review of medical physiology, 23rd edition, page: 533
Category: Physiology
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