Thrombolytic therapy with streptokinase is contraindicated in all of the following except :
**Core Concept**
Thrombolytic therapy involves the use of medications to dissolve blood clots. **Streptokinase** is a thrombolytic agent that works by activating the body's own fibrinolytic system. It is used to treat conditions such as acute myocardial infarction and pulmonary embolism.
**Why the Correct Answer is Right**
Since the correct answer is not provided, let's discuss the general principles of thrombolytic therapy with **streptokinase**. This medication is contraindicated in certain situations where the risk of bleeding outweighs the potential benefits. However, in cases where there is a clear indication for thrombolysis and no absolute contraindications, **streptokinase** can be a lifesaving treatment.
**Why Each Wrong Option is Incorrect**
**Option A:** Typically, recent trauma or surgery is a contraindication for thrombolytic therapy due to the increased risk of bleeding.
**Option B:** Active bleeding is also a contraindication for the same reason.
**Option C:** Intracranial hemorrhage is an absolute contraindication due to the high risk of further bleeding.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **streptokinase** is an antigenic substance that can induce an immune response, leading to the formation of antibodies. This limits its repeated use in the same patient.
**Correct Answer:** Not provided in the query.