Drug which is contraindicated before 2nd stage of labor is: March 2009
💡 Explanation
**Core Concept**
The question tests the understanding of the timing and safety of administering certain drugs in the context of labor stages. The correct answer is related to a medication used to induce anesthesia or analgesia during childbirth.
**Why the Correct Answer is Right**
The correct answer is **Roussel Uclaf factor** (also known as **Roussel Uclaf Factor I** or **RU-486**), which is another name for **Mifepristone**. However, this is not the correct answer. Mifepristone is actually not the correct answer. The correct answer is actually **Pethidine (Meperidine)**. Pethidine is an opioid analgesic that is contraindicated before the second stage of labor because it can cause the baby to become dependent on opioids, leading to neonatal respiratory depression.
**Why Each Wrong Option is Incorrect**
**Option A:** **Mifepristone** is a medication used for medical abortion and is not contraindicated before the second stage of labor.
**Option B:** **None** of the options provided match this description.
**Option C:** **None** of the options provided match this description.
**Option D:** **None** of the options provided match this description.
**Clinical Pearl / High-Yield Fact**
Opioids like Pethidine can cause neonatal respiratory depression due to their ability to cross the placental barrier and bind to opioid receptors in the fetus.