Which of the following vaccine is contraindicated in children with egg allergy
Wait, the MMR vaccine uses chick embryo cells, but it's not made with eggs. The influenza vaccine is produced in eggs, so it might have ovalbumin. The yellow fever vaccine is also grown in chicken embryos, but does it contain egg proteins? I think some sources say that the yellow fever vaccine is contraindicated in egg allergies, but others might say it's safe because the amount of egg protein is minimal. Wait, the question is about contraindicated vaccines. So which ones are contraindicated?
Also, the CDC guidelines: for egg allergies, the flu vaccine is not contraindicated now. They recommend it even for those with severe egg allergies, as long as they can tolerate egg-containing foods. But maybe older guidelines said otherwise. The user's options are missing, but the correct answer is probably influenza vaccine. But I need to make sure. Let me check.
Another vaccine that comes to mind is the rabies vaccine, but I don't think it's egg-based. The yellow fever vaccine is grown in chicken embryos, but the contraindication for egg allergy is a bit unclear. Some sources mention that it's contraindicated in individuals with a history of anaphylaxis to eggs. So maybe the correct answer is yellow fever vaccine? Or influenza?
Wait, the question is about children. The influenza vaccine is commonly given to children. The CDC states that the flu vaccine is not contraindicated in egg-allergic children. However, the yellow fever vaccine is contraindicated in those with egg allergies. So if one of the options is yellow fever vaccine, that would be correct. But the options are A, B, C, D with no specifics given. Hmm. The user's original question must have specific options, but they are missing. Wait, maybe the correct answer is influenza vaccine, but according to current guidelines, it's not contraindicated. So maybe the correct answer is yellow fever vaccine. Let me confirm.
Looking up: The yellow fever vaccine is contraindicated in individuals with a history of anaphylaxis to eggs. The influenza vaccine is not contraindicated. So if the options include yellow fever vaccine, then that's the correct answer. However, if the options are older, maybe they include influenza. But the current answer should be yellow fever. So I need to structure the explanation accordingly. The core concept is about vaccines with egg proteins. The correct answer is yellow fever vaccine (if it's an option). But since the options are missing, maybe the user intended to have options with influenza and yellow fever. Assuming that, the explanation would focus on yellow fever being contraindicated in egg allergy.
**Core Concept**
Vaccines contraindicated in egg-allergic individuals are those containing significant ovalbumin (egg protein). This includes vaccines cultured in eggs, such as yellow fever and influenza vaccines, though current guidelines often allow influenza vaccine in egg-allergic patients due to low allergen content.
**Why the Correct Answer is Right**
The **yellow fever