Contracted kidneys are seen in all of the following diseases except
## Core Concept
The question assesses knowledge of renal pathology, specifically conditions leading to contracted kidneys. Contracted kidneys are typically seen in conditions that cause chronic damage or inflammation, leading to scarring and shrinkage of the kidney tissue.
## Why the Correct Answer is Right
Diabetic nephropathy (Option C) is a complication of diabetes that can lead to chronic kidney disease and eventually to end-stage renal disease. However, it characteristically causes enlarged kidneys due to the accumulation of extracellular matrix proteins and hyperfiltration-induced glomerular damage, rather than contracted kidneys.
## Why Each Wrong Option is Incorrect
* **Option A:** Chronic glomerulonephritis can lead to contracted kidneys due to scarring and inflammation from prolonged immune complex deposition.
* **Option B:** Hypertensive nephrosclerosis results from long-standing hypertension causing damage to the small blood vessels in the kidneys, leading to fibrosis and contraction of the kidneys.
* **Option D:** Chronic pyelonephritis can cause scarring and contraction of the kidneys, especially if the infection is recurrent or persistent.
## Clinical Pearl / High-Yield Fact
A key point to remember is that diabetic nephropathy typically presents with **enlarged** kidneys, not contracted ones, due to the accumulation of matrix proteins. This is a distinguishing feature from other causes of chronic kidney disease.
## Correct Answer: . Diabetic nephropathy