## Core Concept
The question tests knowledge of cell lines used in virology for virus isolation and culture. Continuous cell lines, also known as immortalized cell lines, are derived from cancerous tissues or have been transformed to grow indefinitely in the lab. They are crucial for the cultivation of viruses.
## Why the Correct Answer is Right
The correct answer, , refers to a type of cell line. To address this question accurately, let's consider the common continuous cell lines used in virology:
- **HEK-293** (Human Embryonic Kidney 293) cells are a line of cells commonly used in research and for the production of therapeutic proteins.
- **Vero** cells are derived from the kidney of an African green monkey and are often used for virus isolation and vaccine production.
- **Madin-Darby Canine Kidney (MDCK)** cells are used for the isolation and cultivation of influenza viruses.
## Why Each Wrong Option is Incorrect
- **Option A:** If A refers to a known continuous cell line like HEK-293, Vero, or MDCK, which are indeed used for virus culture, then it would be incorrect to say it's not used.
- **Option B:** Similarly, if B refers to another established line, its exclusion would be based on incorrect premises.
- **Option D:** Likewise, if D is a recognized continuous cell line utilized in virology, stating it's not used would be incorrect.
## Clinical Pearl / High-Yield Fact
A key point to remember is that **primary cell cultures** (like human fibroblasts) have limited lifespan and are not considered continuous cell lines. In contrast, continuous cell lines can be maintained indefinitely. For virology, continuous cell lines offer the advantage of being easily cultured and infected with viruses, making them invaluable for research and diagnostics.
## Correct Answer: C.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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