Content of citrate in ORS is……………millimoles ?
**Core Concept**
The **Oral Rehydration Solution (ORS)** is a type of fluid replacement used to prevent and treat **dehydration**, especially due to **diarrhea**. The composition of ORS is crucial for its effectiveness, including the concentration of **electrolytes** such as **sodium**, **potassium**, and **citrate**.
**Why the Correct Answer is Right**
The correct concentration of **citrate** in ORS is important for helping the body absorb **sodium** and for correcting **acid-base imbalance**. **Citrate** acts as a **base** and helps in the treatment of **metabolic acidosis**, which can occur due to severe diarrhea. The World Health Organization recommends a specific formulation for ORS that includes a particular concentration of **citrate**.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the concentration is not aligned with the WHO recommendations for ORS.
**Option B:** Similarly, this option does not match the recommended concentration of **citrate** in ORS.
**Option D:** This option is also incorrect as it does not correspond to the standard formulation of ORS.
**Clinical Pearl / High-Yield Fact**
It's crucial to remember that the composition of ORS can affect its efficacy and safety. The correct concentration of **electrolytes**, including **citrate**, is vital for the effective treatment of dehydration and the prevention of complications such as **hypokalemia** or **hypernatremia**.
**Correct Answer:** C. 10 millimoles