**Question:** Normal vision with absence of direct & consensual light reflex, which nerve is involved -

A. Optic Nerve
B. Trigeminal Nerve
C. Oculomotor Nerve (III)
D. Abducens Nerve (VI)

**Correct Answer:** C. Oculomotor Nerve (III)

**Core Concept:** The oculomotor nerve (III), also known as the trochlear nerve, is a cranial nerve responsible for the innervation of several ocular muscles, including the rectus muscles responsible for eye movement and the pupillary sphincter.

**Why the Correct Answer is Right:** The oculomotor nerve (III) is responsible for the innervation of the rectus muscles and the pupillary sphincter, which is essential for maintaining normal vision. In the absence of direct and consensual light reflexes, it indicates a lesion involving the oculomotor nerve (III). The direct light reflex is controlled by the oculomotor nerve (III), while the consensual light reflex is controlled by the parasympathetic innervation of the pupil.

**Why Each Wrong Option is Incorrect:**

A. Optic Nerve: The optic nerve (II) is responsible for vision and is not directly related to eye movement or light reflexes.

B. Trigeminal Nerve: The trigeminal nerve (V) is responsible for sensory functions and motor control of the face, not eye movement or light reflexes.

D. Abducens Nerve (VI): The abducens nerve (VI) is responsible for lateral gaze and abduction of the eye, but it is not directly involved in maintaining light reflexes or eye movement.

**Clinical Pearl:**

In clinical practice, assessing the direct and consensual light reflexes is crucial in evaluating the integrity of the oculomotor nerve (III) and other cranial nerves. A lesion involving the oculomotor nerve (III) can present with ptosis, pupillary abnormalities, and gaze palsy. This can help clinicians identify the etiology and guide treatment decisions in patients with neurological symptoms.