**Core Concept**
The question is testing the knowledge of teratogenic effects of certain medications on fetal development. The underlying principle being tested is the ability to identify a specific drug that can cause congenital anomalies such as cleft lip and palate, and atrial septal defect when consumed by a pregnant woman.
**Why the Correct Answer is Right**
The correct answer is a known teratogen that can cause cleft lip and palate, as well as cardiac anomalies, including atrial septal defect. The mechanism of teratogenesis is thought to involve interference with the normal development of the facial and cardiac structures during embryogenesis. Specifically, the drug inhibits the action of sonic hedgehog signaling pathway, which is crucial for the development of the face and heart.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is not a known teratogen associated with cleft lip and palate, and atrial septal defect.
* **Option B:** This option is incorrect because it is not commonly associated with the specific congenital anomalies mentioned in the question.
* **Option C:** This option is incorrect because it is not a known teratogen that can cause cleft lip and palate, and atrial septal defect.
**Clinical Pearl / High-Yield Fact**
It is essential for healthcare providers to be aware of the teratogenic potential of certain medications and to counsel pregnant women about the risks associated with their use.
**Correct Answer: C. Warfarin. Warfarin is a known teratogen that can cause congenital anomalies such as cleft lip and palate, and atrial septal defect when consumed by a pregnant woman.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.