**Core Concept**
The fetus of a diabetic woman is at increased risk of congenital anomalies due to the altered intrauterine environment. Hyperglycemia in the mother leads to increased glucose levels in the fetus, which stimulates excessive insulin production. This results in accelerated growth and development, but also disrupts normal morphogenesis.
**Why the Correct Answer is Right**
The characteristic congenital anomalies in the fetus of a diabetic woman are primarily due to the teratogenic effects of hyperglycemia and hyperinsulinemia. These anomalies include:
* Cardiac defects, such as ventricular septal defects and tetralogy of Fallot
* Neural tube defects, such as spina bifida and anencephaly
* Caudal regression syndrome, characterized by abnormalities of the lower spine and limbs
* Limb reduction defects, including phocomelia and Poland syndrome
* Omphalocele and gastroschisis, which are types of abdominal wall defects
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not specified, so we cannot evaluate its correctness.
* **Option B:** Although not a characteristic congenital anomaly in the fetus of a diabetic woman, other maternal medical conditions, such as phenylketonuria or certain infections, can cause similar anomalies.
* **Option C:** This option is not specified, so we cannot evaluate its correctness.
* **Option D:** This option is not specified, so we cannot evaluate its correctness.
**Clinical Pearl / High-Yield Fact**
The risk of congenital anomalies in the fetus of a diabetic woman is significantly increased, with a four- to seven-fold increase in the risk of major congenital anomalies compared to non-diabetic women. Early prenatal care and tight glycemic control can help minimize this risk.
**Correct Answer:** A.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.