**Question:** In a patient with NIDDM which of the following condition is seen:

A. Impaired Glucose Tolerance (IGT)
B. Impaired Glucose Regulation (IGR)
C. Impaired Glucose Absorption (IGA)
D. Impaired Glucose Production (IGP)

**Core Concept:**
NIDDM, or Non-Insulin Dependent Diabetes Mellitus, is a type of diabetes mellitus where the body remains insulin-resistant despite the presence of insulin. This condition mainly affects the peripheral tissues, where glucose uptake is impaired, leading to hyperglycemia.

**Why the Correct Answer is Right:**
The correct answer, **Impaired Glucose Tolerance (IGT)**, refers to the condition where an individual's blood glucose levels are higher than normal but not yet high enough to be classified as type 2 diabetes mellitus. IGT occurs as a result of insulin resistance, which is seen in patients with NIDDM.

**Why Each Wrong Option is Incorrect:**

A. **Impaired Glucose Tolerance (IGT)** is the correct answer, so options B, C, and D are incorrect.
B. **Impaired Glucose Regulation (IGR)** is not a correct term for the condition described in NIDDM.
C. **Impaired Glucose Absorption (IGA)** is not relevant to NIDDM, as the issue lies with insulin resistance and glucose production, not absorption.
D. **Impaired Glucose Production (IGP)** refers to reduced or inadequate production of insulin, which is not the primary issue in NIDDM.

**Clinical Pearl:**
In patients with NIDDM, the primary issue is insulin resistance, which affects glucose uptake in peripheral tissues. This resistance, coupled with the normal or increased insulin production from the pancreas, leads to hyperglycemia and the development of type 2 diabetes mellitus. Understanding the pathophysiology of NIDDM is crucial for effectively managing the condition and preventing complications.