Concentric hyperophy of left ventricle is seen in
**Core Concept**
Concentric hypertrophy of the left ventricle refers to an increase in the muscle mass of the left ventricle, characterized by a thickening of the ventricular wall without a corresponding increase in chamber dimensions. This is often a compensatory response to increased afterload, such as in hypertension.
**Why the Correct Answer is Right**
The correct answer is associated with conditions that lead to sustained elevated blood pressure, causing the left ventricle to thicken to maintain adequate cardiac output. This adaptation involves the activation of the renin-angiotensin-aldosterone system (RAAS) and the subsequent increase in angiotensin II levels, which stimulates the production of aldosterone. Aldosterone promotes sodium retention and water reabsorption in the kidneys, leading to increased blood volume and pressure. As a result, the left ventricle undergoes concentric hypertrophy to adapt to the increased afterload.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect as it does not directly relate to the pathophysiology of concentric hypertrophy.
* **Option B:** This option is incorrect as it is associated with conditions that lead to dilatation of the left ventricle, such as volume overload or cardiomyopathy.
* **Option C:** This option is incorrect as it is associated with conditions that lead to eccentric hypertrophy, such as aortic stenosis or hypertrophic cardiomyopathy.
**Clinical Pearl / High-Yield Fact**
It is essential to differentiate between concentric and eccentric hypertrophy as they have distinct clinical implications. Concentric hypertrophy is often seen in patients with hypertension, whereas eccentric hypertrophy is seen in patients with conditions that lead to volume overload. A key clinical finding in concentric hypertrophy is a preserved ejection fraction, whereas eccentric hypertrophy is often associated with a decreased ejection fraction.
**Correct Answer:** C. Aortic stenosis