Among the given options ; iodinated compound present in maximum concentration in thyroid is
First, I recall that the thyroid uses iodine to make thyroid hormones. The main hormones are T3 and T4, which are triiodothyronine and thyroxine, respectively. T4 has four iodine atoms, and T3 has three. But wait, the question is about the concentration in the thyroid tissue itself, not in the blood.
I think the thyroid stores more T4 than T3. The thyroid gland synthesizes thyroglobulin, which is a precursor. When the thyroid needs to release hormones, it breaks down thyroglobulin into T4 and T3. Since T4 is the main hormone stored, it's probably present in higher amounts.
Looking at the options, the answer should be T4. But the options aren't listed, so maybe the options are T3, T4, thyroglobulin, or iodide. Wait, if the options include thyroglobulin, which is a protein, it might be a distractor. But thyroglobulin is the storage form, but when broken down, T4 is more abundant.
Wait, another thought: the thyroid actually stores iodide in the colloid as part of thyroglobulin. But the iodinated compounds would be the hormones. So T4 is the main one. Let me confirm: thyroglobulin is a large protein with multiple iodinated tyrosine residues. When the thyroid releases hormones, it cleaves T4 and T3 from thyroglobulin. Since T4 is the primary hormone stored, its concentration is higher. So the correct answer is T4.
Now, the wrong options: if one of them is thyroglobulin, that's a storage protein but not the active hormone. Iodide is stored as iodide ions, but they're not the compound. T3 is present but in lower concentrations than T4. So the answer must be T4.
**Core Concept**
The thyroid gland primarily synthesizes and stores iodinated tyrosine derivatives as thyroid hormones. *Thyroxine (T4)* is the most abundant iodinated compound in the thyroid gland due to its role as the precursor to the more active *triiodothyronine (T3)*.
**Why the Correct Answer is Right**
The thyroid gland iodinates tyrosine residues in thyroglobulin to form *monoiodotyrosine (MIT)* and *diiodotyrosine (DIT)*. Coupling reactions produce *T4 (two DIT molecules)* and *T3 (one MIT + one DIT)*. T4 is the major hormone stored in the thyroid colloid, as it is synthesized in greater amounts than T3. Only 20% of T4 is converted to T3 in peripheral tissues; the rest is excreted or stored, maintaining higher T4 concentrations in the gland.
**Why Each Wrong Option is Incorrect**
**Option A:** *Thyroglobulin* is the storage protein for iodinated tyrosines but is not itself iodinated in high concentration.
**Option B:** *Iodide (I⁻)* is actively transported into thyroid follicular cells but is oxidized and trapped