Which of the following is triad of complication of massive blood transfusion: March 2011, March 2012
**Core Concept**
Massive blood transfusion is a medical emergency that involves the replacement of a significant portion of a patient's blood volume with blood or blood products. This can lead to various complications due to the dilutional effects on coagulation factors, acid-base balance, and electrolyte levels.
**Why the Correct Answer is Right**
The triad of complications associated with massive blood transfusion includes:
- **Dilutional coagulopathy**: This occurs due to the dilution of coagulation factors, platelets, and fibrinogen in the blood, leading to impaired clotting.
- **Metabolic acidosis**: Massive blood transfusion can lead to a significant increase in lactate levels and a decrease in pH due to the citrate preservative in stored blood.
- **Hypothermia**: Blood transfusions can rapidly lower the recipient's body temperature, leading to hypothermia.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately represent the triad of complications associated with massive blood transfusion.
**Option B:** This option is incorrect because it is a different set of complications, such as transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and hemolytic transfusion reaction.
**Option C:** This option is incorrect because it is not a recognized complication of massive blood transfusion.
**Clinical Pearl / High-Yield Fact**
Remember the "3 Ds" of massive blood transfusion complications: dilutional coagulopathy, metabolic acidosis, and hypothermia.
**Correct Answer:** C. Dilutional coagulopathy, Metabolic acidosis, and Hypothermia