Patient presents with complaints of lower abdominal pain, fever and repeated stools with little faecal matter and blood and mucus. On microscopy paucity of WBCs in stool with positive test for heme. Which is the likely organism?
First, the symptoms point towards an infectious colitis. The presence of blood and mucus suggests an inflammatory process. But the stool has few white blood cells. That's interesting because in bacterial infections like Shigella or E. coli, you usually see a lot of WBCs. So if there are few WBCs, maybe it's a different organism.
The heme test is positive, which detects blood. So the organism must be causing bloody diarrhea. Let's consider the options. The question didn't provide the options, but common organisms for dysentery include Shigella, E. coli (like EHEC), Salmonella, Campylobacter, and maybe parasites like Entamoeba histolytica.
Wait, Entamoeba histolytica is a protozoan. Its infection can cause dysentery with blood and mucus, but the stool might have fewer WBCs compared to bacterial infections. Also, in amebic dysentery, you might see characteristic trophozoites in the stool, but if the sample is not fresh, they might not be visible. The heme test would be positive here as well. So maybe the answer is Entamoeba histolytica.
Alternatively, C. difficile is another possibility, but that's more associated with pseudomembranous colitis after antibiotic use, and the presentation might be different. Shigella and E. coli would have more WBCs. Salmonella usually causes more watery diarrhea. So the paucity of WBCs points more towards a non-bacterial cause, like amoebiasis.
So the likely organism here is Entamoeba histolytica. The key points are the symptoms of dysentery with blood and mucus, few WBCs in stool, and positive heme. The other options don't fit as well because of the WBC count.
**Core Concept**
This question tests the differential diagnosis of dysentery, focusing on the distinction between bacterial and parasitic causes based on stool findings. **Entamoeba histolytica** is a protozoan that causes amebic dysentery, characterized by **paucity of white blood cells (WBCs)** in stool and **positive heme test** due to mucosal ulceration. In contrast, bacterial causes like **Shigella** or **Campylobacter** typically show **increased WBCs** in stool.
**Why the Correct Answer is Right**
**Entamoeba histolytica** infects the colon, causing flask-shaped ulcers with **blood and mucus**. The paucity of WBCs occurs because the parasite directly invades the mucosa, bypassing the need for a robust inflammatory response (unlike bacteria). The **heme test** detects blood from mucosal erosion, while **trophozoites** may be seen in fresh stool. Amebiasis is more common in areas with poor sanitation and can lead to liver abscesses if untreated.
**Why Each Wrong Option is Incorrect**
**Option A:** *Shigella*