Commonest histological finding in benign hypeension is aEUR’
Correct Answer: Hyaline aeriosclerosis
Description: Hyaline aeriosclerosis Hyaline aeriosclerosis consists of homogenous pink hyaline thickening of the wall of the aerioles with loss of underlying structural detail. Encountered .frequently in elderly patients whether normotensive or hypeensive, hyaline aeriosclerosis is more generalized and more severe in patients with hypeensiondeg. It is also common in diabetesdeg as a pa of the characteristic microangiopathy. Pathogenesis The lesion reflects leakage of plasma components across vascular endothelium and excessive extracellular matrix production by smooth muscle cells secondary to the chronic hemodynamic stress of hypeension or a metabolic stress in diabetes that accentuates endothelial cell injury. Also know Hyperplastic aeriosclerosis It is characteristic of malignant hypeensionQ. There is concentric laminated thickening of aeriolar wall onion thickenine There is mucinous intimal thickening and fibrous intimal thickening. There may be accompanied .fibrinoid deposite with necrosis of the vessel wall --,vfibrinoid necrosisQ.
Category:
Pathology
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