Commonest cause of first trimester aboion is:
**Core Concept:**
First trimester abortion is a common complication in early pregnancy. The correct answer relates to the underlying cause of spontaneous abortion, which is the involuntary termination of a pregnancy before the fetus reaches a viable stage. The correct answer involves miscarriage, which occurs when a pregnancy does not progress beyond the first trimester (up to 12 weeks). The human placenta is essential for the continuation of pregnancy, and its failure can lead to miscarriage.
**Why the Correct Answer is Right:**
The correct answer, **Option D:** "Improperly formed placenta" refers to placental insufficiency, which is the inadequate supply of oxygen and nutrients to the fetus due to abnormal placental development or structure. This can lead to miscarriage as the placenta's primary role is to support the fetus and maintain the pregnancy.
Improperly formed placenta can result from various reasons, including:
1. Placental ischemia: Insufficient blood supply to the placenta, often caused by uterine artery stenosis or uterine malformations.
2. Placental infarction: Partial or complete death of placental tissue due to blood flow obstruction or placenta abruption.
3. Placental abruption: Separation of the placenta from the uterine wall, leading to acute hemorrhage and potentially miscarriage.
4. Placental maldevelopment: Abnormal placental structure or size due to maternal factors or genetic abnormalities.
**Why Each Wrong Option is Incorrect:**
**Option A:** "Placenta previa" refers to the implantation of the placenta too low in the uterus, causing placental bleeding during childbirth. This is not a cause of miscarriage in the first trimester.
**Option B:** "Placental abruption" is a cause of severe bleeding during childbirth, not first trimester miscarriage.
**Option C:** "Placental infarction" is a cause of acute hemorrhage during labor, not first trimester miscarriage.
**Option E:** "Placental abruption" is a cause of severe bleeding during childbirth, not first trimester miscarriage.
**Option F:** "Placental abruption" is a cause of severe bleeding during childbirth, not first trimester miscarriage.
**Option G:** "Placental abruption" is a cause of severe bleeding during childbirth, not first trimester miscarriage.
**Option H:** "Placental abruption" is a cause of severe bleeding during childbirth, not first trimester miscarriage.
**Clinical Pearl:**
In cases of placental abruption, the placenta detaches from the uterine wall prematurely, leading to acute bleeding and severe complications during childbirth. In contrast, miscarriage occurs due to placental issues in early pregnancy.
**Why Option D is Right:**
Placental abruption is a cause of severe bleeding during childbirth, while miscarriage occurs