**Core Concept**
Mendelian inheritance refers to the transmission of traits from parents to offspring according to the laws of Mendel, which describe the behavior of genes in simple, predictable patterns. This includes autosomal dominant, autosomal recessive, and sex-linked inheritance patterns.
**Why the Correct Answer is Right**
The most common Mendelian disorder is autosomal dominant conditions, which occur when a single copy of the disease-causing gene is sufficient to cause the condition. This is because autosomal dominant disorders have a high penetrance and express in every generation, making them more likely to be encountered in clinical practice. For example, conditions like achondroplasia, neurofibromatosis type 1, and Huntington's disease are all autosomal dominant disorders.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not specified, so we cannot provide an incorrect explanation.
**Option B:** While autosomal recessive disorders are also common, they are less likely to be encountered in clinical practice due to the need for two copies of the disease-causing gene.
**Option C:** Sex-linked disorders, such as hemophilia, are relatively rare and typically affect males more frequently than females.
**Clinical Pearl / High-Yield Fact**
Autosomal dominant disorders often present with variable expression and penetrance, making them challenging to diagnose and manage. A key concept to remember is that individuals with autosomal dominant disorders have a 50% chance of passing the disease-causing gene to each offspring.
**Correct Answer: A. Autosomal dominant disorders are the most common Mendelian inheritance pattern.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.