Combination chemotherapy is used in tuberculosis in order to reduce:?
Correct Answer: Development of drug resistance
Description: Combination therapy:
Like in the case of TB, leprosy, HIV and malaria, combination therapy with 2 effective drugs has several advantages in the treatment of VL. These are:
Limiting risk of development of drug resistance, thereby prolonging the effective life-time of available medicines.
Attaining higher efficacy and cure rate.
Shortening of duration of therapeutic regimen; better compliance and convenience.
Reduction of overall dose; lower toxicity and cost.
Reference: Essentials of Medical Pharmacology Seventh Edition KD TRIPATHI page no 847
Category:
Pharmacology
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