**Collagen 17**
**Core Concept**
Collagen 17 is a type of collagen that plays a crucial role in the formation and maintenance of the skin's basement membrane, particularly in the epidermal-dermal junction. It is a transmembrane collagen that helps to anchor the epidermis to the dermis, thereby providing structural support to the skin.
**Why the Correct Answer is Right**
Collagen 17 is a transmembrane protein that spans the basement membrane, interacting with integrins and other proteins to form a stable complex. This interaction is essential for maintaining the integrity of the skin and preventing conditions such as epidermolysis bullosa. The correct answer is a key component of the skin's extracellular matrix.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because collagen 17 is not a type of collagen that is primarily associated with bone or cartilage formation.
**Option B:** This option is incorrect because collagen 17 is not a type of collagen that is involved in blood clotting.
**Clinical Pearl / High-Yield Fact**
Remember that collagen 17 is a transmembrane collagen that plays a critical role in maintaining the skin's basement membrane. This is an important concept for understanding the pathophysiology of skin disorders such as epidermolysis bullosa.
**Correct Answer:** C.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.