Coicosteroid which is given by inhalation route is-
**Core Concept**
The question is testing the student's knowledge of inhaled corticosteroids, which are a class of medications used to manage asthma and chronic obstructive pulmonary disease (COPD) by reducing airway inflammation. Inhaled corticosteroids work by binding to glucocorticoid receptors in the lungs, which triggers a cascade of anti-inflammatory effects.
**Why the Correct Answer is Right**
The correct answer is **Fluticasone****. It is a synthetic corticosteroid that is commonly used in inhalers to control asthma symptoms and prevent exacerbations. Fluticasone works by binding to glucocorticoid receptors in the lungs, which downregulates the expression of pro-inflammatory genes and reduces airway inflammation. This leads to improved lung function, reduced symptoms, and improved quality of life for patients with asthma.
**Why Each Wrong Option is Incorrect**
* **Option A:** Beclomethasone is another inhaled corticosteroid, but it is not the most commonly used one.
* **Option B:** Budesonide is an inhaled corticosteroid, but it is not the correct answer.
* **Option D:** Triamcinolone is a systemic corticosteroid, not an inhaled one.
**Clinical Pearl / High-Yield Fact**
Inhaled corticosteroids are the first-line treatment for asthma and COPD, and they should be used at the lowest effective dose to minimize side effects. Fluticasone is a popular choice because of its high potency and low systemic absorption.
**Correct Answer:** C. Fluticasone