True about coding strand of DNA:
**Question:** What is true about the coding strand of DNA?
**Core Concept:** DNA (Deoxyribonucleic Acid) is a molecule that carries the genetic information of an organism. It consists of two strands (helices) that are complementary, meaning each nucleotide of one strand is paired with a specific nucleotide of the other strand. The coding strand is the strand that carries the genetic information, while the non-coding strand does not have a specific role in coding but is involved in maintaining the integrity of the DNA molecule.
**Why the Correct Answer is Right:** The correct answer is C, which states that the coding strand is the one that carries the genetic information. This is because the coding strand contains the genetic information in the form of the primary structure, which is transcribed into RNA (Ribonucleic Acid) during transcription, leading to the formation of messenger RNA (mRNA) molecules that carry the genetic information to the cell's ribosomes for protein synthesis.
**Why Each Wrong Option is Incorrect:**
A. This option incorrectly states that the coding strand is the non-coding strand. As explained earlier, the coding strand carries the genetic information, not the non-coding strand.
B. This option incorrectly states that the coding strand is the non-coding strand. As explained earlier, the coding strand carries the genetic information, not the non-coding strand.
D. This option incorrectly states that the coding strand is the template strand. While it is true that the coding strand serves as a template for transcription, the actual coding information lies in the complementary RNA strand (mRNA).
**Clinical Pearl:** Understanding the relationship between DNA strands, transcription, and protein synthesis is essential for understanding genetics, molecular biology, and the genetic code. This knowledge is relevant for medical students and practicing physicians alike, as it is fundamental to understanding genetic disorders, gene expression, and therapeutic interventions targeting the genetic level.