**Core Concept**
The question tests knowledge of adverse effects related to **lithium therapy**, which is commonly used in the management of **bipolar disorder**. Lithium has a narrow therapeutic index and can cause various side effects due to its impact on multiple physiological systems.

**Why the Correct Answer is Right**
Lithium is known to cause **coarse tremors** as a side effect due to its effects on the **central nervous system**. It can also lead to **polyuria** by decreasing the responsiveness of the **kidneys** to **antidiuretic hormone (ADH)**, resulting in **nephrogenic diabetes insipidus**. Additionally, lithium can interfere with **thyroid function**, leading to **hypothyroidism** in some patients.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the specific combination of side effects mentioned does not typically correlate with the common adverse effect profiles of other medications.
**Option B:** Similarly, this option does not align with the known side effects of other drugs.
**Option C:** This option is also incorrect as it does not match the profile of adverse effects associated with lithium therapy.

**Clinical Pearl / High-Yield Fact**
It's crucial to monitor patients on lithium therapy for signs of **lithium toxicity**, which can be precipitated by factors such as dehydration or renal impairment. Regular assessment of **thyroid function** and **renal function** is also essential.

**Correct Answer:** D. Lithium