Predominantly sensory neuropathy is/are caused by-a) Cisplatinb) Pyridoxine excessc) Diphtheriad) Guillain-Barre syndrome

**Core Concept**
The question tests the understanding of neuropathies, specifically those that are predominantly sensory in nature. **Sensory neuropathy** refers to damage to the sensory nerves, which can lead to symptoms such as numbness, tingling, and pain. Various toxins, deficiencies, and diseases can cause sensory neuropathy.

**Why the Correct Answer is Right**
The correct answer includes **Cisplatin**, a chemotherapeutic agent known to cause **peripheral neuropathy**, particularly affecting sensory nerves. **Pyridoxine excess** can also lead to sensory neuropathy, as high doses of vitamin B6 can be neurotoxic. These conditions highlight the importance of recognizing the potential side effects of certain medications and supplements.

**Why Each Wrong Option is Incorrect**
**Option D:** **Guillain-Barre syndrome** is an autoimmune disorder that predominantly affects motor nerves, leading to muscle weakness and paralysis, making it less likely to be predominantly sensory in nature.

**Clinical Pearl / High-Yield Fact**
It's crucial to remember that certain medications and supplements can have neurotoxic effects, leading to sensory neuropathy. Recognizing these potential side effects can aid in early diagnosis and management.

**Correct Answer:** A, B. Cisplatin, Pyridoxine excess