Ciprofloxacin should not be given to an asthmatic using theophylline because:
Correct Answer: Ciprofloxacin inhibits theophylline metabolism
Description: Ans. (A) Ciprofloxacin inhibits theophylline metabolism(Ref: KDT 8/e p761)Theophylline has a narrow margin of safety (low therapeutic index) Ciprofloxacin inhibits theophylline metabolism and increases its plasma level leading to toxicity. Thus, ciprofloxacin should not be given to an asthmatic using theophylline.
Category:
Pharmacology
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