**Core Concept**
The question is testing the understanding of **genetic disorders** caused by **abnormalities in chromosome inheritance**, specifically **uniparental disomy**. Uniparental disomy occurs when a person receives two copies of a chromosome, or part of a chromosome, from one parent and no copies from the other parent.
**Why the Correct Answer is Right**
**Prader-Willi syndrome** and **Angelman syndrome** are two disorders associated with chromosome 15. However, the specific condition caused by **maternal disomy of chromosome 15** is **Prader-Willi syndrome** is not correct in this context, as it is typically associated with paternal deletion or uniparental disomy. Maternal disomy of chromosome 15 is actually associated with **Angelman syndrome** is not correct in the context of maternal disomy, but **Prader-Willi syndrome** can be associated with maternal uniparental disomy, though more commonly it's paternal in origin issues.
**Why Each Wrong Option is Incorrect**
**Option A:** The condition associated with this option is not the one caused by maternal disomy of chromosome 15.
**Option B:** This condition might be associated with a different genetic mechanism.
**Option D:** This option does not correspond to the disorder caused by maternal disomy of chromosome 15.
**Clinical Pearl / High-Yield Fact**
It's crucial to remember that **uniparental disomy** can lead to various genetic disorders, depending on which chromosome and which parent is involved. For chromosome 15, the parent of origin significantly affects the resulting syndrome.
**Correct Answer:** Correct Answer: B. Prader-Willi syndrome
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