**Core Concept**
Congenital toxoplasmosis is a condition caused by the Toxoplasma gondii parasite, which can be transmitted to the fetus during pregnancy, leading to various manifestations in the newborn, including microcephaly, chorioretinitis, limb hypoplasia, and cicatrising lesions.

**Why the Correct Answer is Right**
The presence of chorioretinitis, a form of eye inflammation, and microcephaly, a condition characterized by a small head size, are classic manifestations of congenital toxoplasmosis. Toxoplasma gondii infection during pregnancy can cause fetal damage, leading to limb hypoplasia and cicatrising lesions. The parasite's ability to cross the placenta and infect the fetus is facilitated by its ability to evade the maternal immune system.

**Why Each Wrong Option is Incorrect**
**Option A:** **Tuberous Sclerosis Complex** - While this condition can cause various systemic manifestations, including skin lesions and eye abnormalities, it is not typically associated with the specific combination of microcephaly, chorioretinitis, and limb hypoplasia presented in this case.
**Option B:** **Congenital Rubella** - Although congenital rubella can cause a range of manifestations, including eye abnormalities and limb hypoplasia, it is not characteristically associated with the specific pattern of chorioretinitis and cicatrising lesions seen in this case.
**Option C:** **Zika Virus Infection** - Zika virus can cause congenital abnormalities, including microcephaly, but it is not typically associated with the combination of chorioretinitis, limb hypoplasia, and cicatrising lesions presented in this case.

**Clinical Pearl / High-Yield Fact**
Congenital toxoplasmosis can be prevented by avoiding exposure to cat feces during pregnancy and taking appropriate measures to reduce the risk of transmission.

**Correct Answer:** D. **Toxoplasmosis**