Choose the one best answer that most accurately describes some properties of acetyl-CoA carboxylase.
Correct Answer: Required Cofactor - Biotin; Intracellular Location - Cytoplasmic; Allosteric Modifier - Citrate; Enzyme That Catalyzes a Covalent Modification - AMP-activated protein kinase
Description: Biotin is required for the acetyl-CoA carboxylase reaction in which the substrate, acetyl-CoA, is carboxylated by the addition of CO2 to form malonyl-CoA. This reaction occurs in the cytosol. Malonyl-CoA provides the C-2 units that add to the growing fatty acid chain on the fatty acid synthase complex. As the growing chain is elongated, malonyl-CoA is decarboxylated. Citrate is an allosteric activator of the enzyme, and the enzyme is inhibited by phosphorylation by the AMP-activated protein kinase.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now