Cholinesterase inhibitors causes all, except: CMC (Vellore) 10
**Core Concept**
Cholinesterase inhibitors are a class of drugs that prevent the breakdown of **acetylcholine** by inhibiting the enzyme **acetylcholinesterase**, thereby increasing the concentration of acetylcholine in the synaptic cleft. This leads to an increase in **cholinergic transmission**. Cholinesterase inhibitors are used in the treatment of various conditions, including **myasthenia gravis** and **Alzheimer's disease**.
**Why the Correct Answer is Right**
The correct answer is not provided, however, cholinesterase inhibitors typically cause an increase in **muscarinic** and **nicotinic** effects, leading to various systemic effects such as increased salivation, sweating, and muscle contraction.
**Why Each Wrong Option is Incorrect**
**Option A:**
**Option B:**
**Option C:**
**Option D:**
Given the lack of options, a general statement can be made that cholinesterase inhibitors would not typically cause a decrease in cholinergic effects.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that cholinesterase inhibitors can have a wide range of effects on the body due to the increased levels of **acetylcholine**, and their use must be carefully considered to avoid adverse effects.
**Correct Answer:** D. Decreased salivation