**Core Concept**
The transport of cholesterol from the liver to peripheral tissues is a critical aspect of lipid metabolism, involving various lipoproteins. The liver synthesizes and secretes lipoproteins, which carry cholesterol and other lipids to peripheral tissues for utilization or storage.

**Why the Correct Answer is Right**
LDL (Low-Density Lipoprotein) is the primary lipoprotein responsible for transporting cholesterol from the liver to peripheral tissues. This process is mediated by the action of apolipoprotein B-100, which binds to LDL receptors on the surface of peripheral tissue cells, facilitating the uptake of cholesterol. The liver also synthesizes and secretes LDL, which is then transported to peripheral tissues via the bloodstream.

**Why Each Wrong Option is Incorrect**
**Option A:** HDL (High-Density Lipoprotein) primarily functions to transport excess cholesterol from peripheral tissues to the liver for excretion, a process known as reverse cholesterol transport.
**Option C:** VLDL (Very-Low-Density Lipoprotein) is primarily involved in the transport of triglycerides from the liver to peripheral tissues, rather than cholesterol.
**Option D:** Chylomicrons are lipoproteins that transport dietary triglycerides from the intestine to the liver and peripheral tissues, but are not primarily involved in the transport of cholesterol from the liver.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that high levels of LDL cholesterol are associated with increased risk of atherosclerotic cardiovascular disease, making LDL a key target for lipid-lowering therapies.

**✓ Correct Answer: B. LDL. LDL is the primary lipoprotein responsible for transporting cholesterol from the liver to peripheral tissues.**