Microbiology Cholera toxin acts by which mechanism? A Overactivates adenylate cyclase (cAMP) by permanently activating Gs B Mimics the adenylate cyclase enzyme (cAMP) C Overactivates guanylate cyclase (cGMP) D Inactivate elongation factor (EF-2) 💡 Explanation Cholera toxin acts by which mechanism? ✓ Correct Answer: A. Overactivates adenylate cyclase (cAMP) by permanently activating Gs