Regarding cholecystokinin-pancreozymin (CCK-PZ), all are true except (Repeat 2007 Q 42)
**Core Concept**
Cholecystokinin-pancreozymin (CCK-PZ), also known as secretin, is a hormone that plays a crucial role in the digestion process. It is released by the duodenum in response to the presence of nutrients, particularly fat, and stimulates the release of pancreatic enzymes and bile from the gallbladder.
**Why the Correct Answer is Right**
CCK-PZ acts on the gallbladder to contract and release bile into the common bile duct, which then flows into the duodenum. This process enhances the emulsification of fats, allowing for more efficient absorption of fat-soluble vitamins. CCK-PZ also stimulates the pancreas to release digestive enzymes, such as amylase, lipase, and trypsin, which break down carbohydrates, fats, and proteins, respectively.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because CCK-PZ is not primarily responsible for stimulating the release of insulin.
**Option B:** This option is incorrect because CCK-PZ does not directly stimulate the release of gastrin.
**Option C:** This option is incorrect because CCK-PZ does not directly stimulate the release of gastric acid.
**Clinical Pearl / High-Yield Fact**
A key function of CCK-PZ is to regulate the digestive process by stimulating the release of pancreatic enzymes and bile, which is essential for fat emulsification and absorption.
**Correct Answer: B.**