**Core Concept**
Chlorpromazine is a typical antipsychotic medication primarily used to treat schizophrenia. Its antidopaminergic property, specifically blocking D2 receptors in the mesolimbic pathway, contributes to its therapeutic effects. However, chlorpromazine also exhibits other pharmacological actions that are not solely due to its antidopaminergic properties.
**Why the Correct Answer is Right**
Chlorpromazine's antidopaminergic effects primarily account for its antipsychotic and antiemetic properties. However, its anticholinergic activity, which results from blocking muscarinic acetylcholine receptors, is responsible for secondary effects such as dry mouth, blurred vision, and constipation. Additionally, chlorpromazine has a moderate level of alpha-adrenergic blockade, contributing to its hypotensive effects.
**Why Each Wrong Option is Incorrect**
**Option A:** Not directly related to chlorpromazine's mechanism of action.
**Option B:** Incorrect, because chlorpromazine does have some anticholinergic properties, even though its primary action is not through this mechanism.
**Option C:** Incorrect, because chlorpromazine does exhibit some level of alpha-adrenergic blockade, contributing to its hypotensive effects.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that antipsychotic medications like chlorpromazine can exhibit multiple pharmacological actions beyond their primary antidopaminergic effects, which can lead to various side effects and drug interactions.
**Correct Answer: D.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.