Child admitted with meningitis. Examination reveals gram negative diplococci. History of previous similar infection is present with same organism. Which of the following should be suspected?
Correct Answer: Complement deficiency
Description: Ans: A (Complement deficiency) Ref: Harrison's Principles of Internal Medicine, 17th edition, 2008, Chapter 136, pg: 911 and Nelson Textbook of Pediatrics, 19th editionExplanation:Defects in Complement SystemHost DefectDisease or Therapy Associated With DefectCommon Etioiogic Agent of InfectionC3* Congenital liver disease* SLE* Nephrotic syndrome* S. aureus* S. pneumoniae* Pseudomonas spp* Proteus spc.C5* Congenital* Neisseria spp.* Gram-negative rodsC6,C7,C8* Congenital,* SLE* Neisseria meningitidis* N. qonorrhoeaeAlternativepathway* Sickie cell disease* S. pneumonia* Salmonella spp.
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